NOVOPLASM

CTIBIOTECH, together with the French Army, Ecole Polytechnique, Paris (the official university of the army) and Institut Pasteur were successful in gaining a rare funded project of the French government - called ASTRID, at @1.2 Million Euros. With this we made highly sophisticated 3D bioprinted human skin with immune cells inside and used this to test (i) the infiltration of dangerous bacteria (S. aureus) into the skin, and to see if the immune system could recognise it and fight it. We then used a cold plasma machine designed at the university of the army to develop its capacity to sterilise the skin. SIGNIFICANCE: patients who are in hospital for a long time can get ulcers or bedsores. We are helping to find solutions to help them. Also when people get burns, we have to find ways to sterilise the burn without touching it. This is an example of translational medical research in action!

INNOVATION

CTI

3/11/20251 min read

CTIBIOTECH skin models are designed to be flexible to allow different cell types or elements to be included. In the NOVOPLASM project a complex model with immune system was made and then infected with S. aureus bacteria at INSTITUT PASTEUR in Paris. Then the cold plasma device created at the Army university platform LPP was used to see if there were possibilities to sterilise the bacteria. This is part of a larger project to sterilise burns and wounds without touching the skin.

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